In high concentrations (30-60mg), nicotine is neurotoxic, deterrent to insects and lethal to humans. On the other hand, in smaller doses (1mg in every cigarette stick), it acts as a stimulant.
Nicotine Detection Testing
Affecting mostly the nervous system, nicotine decreases the appetite, boosts mood, relieves depression, enhances brain activity, and improves cognition and memory. However, it also stimulates intestinal motility, increases salivation, increases both the heart rate and blood pressure, and may even cause nausea and vomiting.
It only takes one milligram of nicotine per one cigarette stick to stimulate the brain, but this would be enough to cause cigarette smoking-induced nicotine addiction.
Nicotine use may not only be proven based on one's symptoms, a number of diagnostics are now available to detect nicotine in the body.
When one smokes, nicotine inhaled is then metabolized into cotinine in organs such as the lungs and the liver, and subsequently excreted in the urine. Aside from nicotine, cotinine is a reliable biomarker and indicator for nicotine use, detectable in the blood, urine, and saliva.
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